Author

Isaac Brownell

National Institute of Arthritis and Musculoskeletal and Skin DiseasesORCID 0000-0002-0090-9914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Athena SchepmoesiD· 1 shared Ben DruckeriD· 1 shared Brianna I. GonzaleziD· 1 shared Clifton L. DalgardiD· 1 shared Craig D. ShriveriD· 1 shared David Ross HalliD· 1 shared Elaine S. KeungiD· 1 shared Heidi H. KongiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Athena SchepmoesORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 16, 2026

Detection of Melanoma Using Deep Serum Proteome Profiling and Machine Learning

David Ross Hall, Brianna I. Gonzalez, Athena Schepmoes…·Tao Liu

This study detects melanoma using serum proteome profiling and machine learning, identifying eight protein biomarkers with high diagnostic accuracy.

DOI 10.64898/2026.06.11.731698

humanproteomics

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GenomicsbioRxivPreprintOct 21, 2024

Estimating and correcting index hopping misassignments in single-cell RNA-seq data

Lingling Miao, Loren Collado, Savannah Barkdull…·Isaac Brownell

The paper estimates and corrects index hopping misassignments in scRNA-seq data by analyzing signature genes across cell types and adjusting expression levels.

DOI 10.1101/2024.10.21.619353

mousescRNA-seq

𝕏 PostBluesky