MLL3/MLL4 enzymatic activity shapes DNA replication timing
Deniz Gökbuget, Ryan M. Boileau, Kayla Lenshoek, Robert H. Blelloch
The paper identifies MLL3/MLL4 enzymatic activity as a regulator of DNA replication timing through H3K4me1 modification, showing its role in chromatin structure and replication dynamics during differentiation.
bioRxiv · Dec 7, 2023 · PreprintGenomics