BioinformaticsbioRxivPreprint
Amino acid clustering and epistasis guide sequence-based prediction of phenotype modulation
Ayelen S. Hernandez Berthet, Ignacio E. Sanchez, Martin E. Noguera, Ernesto A. Roman
The paper develops a method to predict phenotype modulation by analyzing amino acid clustering and epistasis in protein sequences, showing that these factors improve prediction accuracy.
DOI 10.64898/2026.11.06.764933