Chromosome-level scaffolding of haplotype-resolved assemblies using Hi-C data without reference genomes
Xiaofei Zeng, Zili Yi, Xingtan Zhang, Yuhui Du, Yu Li, Zhiqing Zhou, Sijie Chen, Huijie Zhao, Sai Yang, Yibin Wang, Guoan Chen
This paper introduces HapHiC, a reference-independent allele-aware scaffolding tool that improves chromosome assignment and contig ordering, and applies it to construct a haplotype-resolved allotriploid genome.
Nature Plants · Aug 5, 2024Peer-reviewedBioinformatics