Author

Ilias Frydas

Aristotle University of ThessalonikiORCID 0000-0002-0133-709XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Birgit MertensiD· 1 shared Bob van de WateriD· 1 shared Carsten WeißiD· 1 shared Dayna R. SchultziD· 1 shared Dimosthenis Andreas SarigiannisiD· 1 shared Elisavet Renieri· 1 shared Emmanuel DemuynckiD· 1 shared Friedel DewulfiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Birgit MertensORCID

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1 paper

Recent·Most cited

Analytical Choices Drive Toxicogenomic Potency Estimates: A Systematic Evaluation of Transcriptomic Points of Departure

Imke B. Bruns, Dayna R. Schultz, Emmanuel Demuynck, Friedel Dewulf, Ioannis Theologidis, Steven J. Kunnen, Lukas S. Wijaya, Ilias Frydas, Nafsika Papaioannou, Elisavet Renieri, Thanasis Papageorgiou, Dimosthenis Andreas Sarigiannis, Kyriaki A. Machera, Birgit Mertens, Jana Asselman, , Giulia Callegaro

The paper evaluates how different transcriptomic analysis workflows affect potency estimates in toxicogenomics, finding significant variability driven by normalization, filtering, and pathway definitions.

Toxicological Sciences · Sep 1, 2026Peer-reviewedBioinformatics