Multivalent adaptor networks generate nanoscale organisation within T cell signalling condensates
Shirin Ansari, Pooja Laxman, James C. Walsh, Zhengmin Yang, Andrea C. Nunez, Jesse Goyette
The paper uses super-resolution imaging to show that TCR and LAT form structured nanoscale condensates in human T cells, with spatial organization that supports multivalent signaling.
bioRxiv · Apr 30, 2026 · PreprintImmunology