Author

Ehud Karavani

Hebrew University of JerusalemORCID 0000-0002-0187-5437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alex Hatzimanolis· 1 shared Aritra BoseiD· 1 shared Danny ZeeviiD· 1 shared Diego Machado ReyesiD· 1 shared Dimitrios AvramopoulosiD· 1 shared Gil AtzmoniD· 1 shared Laxmi ParidaiD· 1 shared Leonid KruglyakiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Alex Hatzimanolis

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2 papers

Recent·Most cited

FairPRS: a fairness framework for Polygenic Risk Scores

Diego Machado Reyes, Aritra Bose, Ehud Karavani, Laxmi Parida

This paper introduces FairPRS, a method to create polygenic risk scores that are fair across ethnic groups by using invariant risk minimization, showing improved phenotype prediction and reduced racial bias.

medRxiv · Aug 28, 2022 · PreprintGenetic & Genomic Medicine

Screening human embryos for polygenic traits has limited utility

Ehud Karavani, Or Zuk, Danny Zeevi, Nir Barzilai, Nikos C. Stefanis, Alex Hatzimanolis, Nikolaos Smyrnis, Dimitrios Avramopoulos, Leonid Kruglyak, Gil Atzmon, Max Lam, Todd Lencz, Shai Carmi

This paper evaluates the potential benefits of using polygenic scores to select embryos for traits like height and cognitive function, finding limited gains with current predictors.

Cell · Nov 1, 2019Peer-reviewedGenetics