Author

Paolo Zaffino

Magna Graecia UniversityORCID 0000-0002-0219-0157Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

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Alessio MerolaiD· 1 shared Anna ProcopioiD· 1 shared Carlo CosentinoiD· 1 shared Francesco AmatoiD· 1 shared Rita Granata· 1 shared

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Alessio MerolaORCID

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1 paper

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Systems BiologybioRxivPreprintOct 16, 2026

Polarization of regulatory inputs reveals structural constraints in reconstructed pathway-associated regulatory networks

Anna Procopio, Rita Granata, Paolo Zaffino…·Carlo Cosentino

The paper introduces a framework to analyze regulatory network polarization and finds that mixed-input targets are systematically depleted in pathway-associated networks.

DOI 10.64898/2026.10.09.758118

statistical modelgene regulatory network inference

𝕏 PostBluesky