Anthracycline-induced cardiotoxicity associates with a shared gene expression response signature to TOP2-inhibiting breast cancer drugs in cardiomyocytes
E. Renee Matthews, Omar D. Johnson, K Horn, José A. Gutiérrez, Simon R. Powell, Michelle C. Ward
The paper investigates the shared gene expression response to TOP2-inhibiting breast cancer drugs in cardiomyocytes and identifies genetic factors associated with inter-individual variation in cardiotoxicity.
PLoS Genetics · Feb 28, 2024Peer-reviewedGenomics