Author

Mauro L. Mugnai

Georgetown UniversityORCID 0000-0002-0267-2279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Dave ThirumalaiiD· 3 shared Dmitrii E. MakaroviD· 1 shared Farkhad MaksudoviD· 1 shared Laura Domı́ngueziD· 1 shared Sucheol ShiniD· 1 shared Yonathan GoldtzvikiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 8 mutual co-author links

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3 shared papersBiophysics

Dave ThirumalaiORCID

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3 papers

Recent·Most cited

Droplet growth, Ostwald's rule, and emergence of order in Fused in Sarcoma

Farkhad Maksudov, Mauro L. Mugnai, Laura Domı́nguez, Dmitrii E. Makarov, Dave Thirumalai

This study investigates the phase separation and assembly of FUS-LC, showing that core regions form in a specific order and that Ostwald's rule applies to their maturation and stability.

Proceedings of the National Academy of Sciences · Jan 23, 2026Peer-reviewedBiophysics

Lever arm Flexibility Controls the extent of (Un)coupling to the Motor Domain in Myosin Motors

Mauro L. Mugnai, Yonathan Goldtzvik, Dave Thirumalai

The paper investigates how lever arm flexibility affects coupling to the motor domain in dimeric myosin motors using theoretical models and chimeric constructs.

The Journal of Physical Chemistry B · Oct 2, 2025Peer-reviewedBiophysics

Water-mediated interactions between glycans are weakly repulsive and unexpectedly long-ranged

Sucheol Shin, Mauro L. Mugnai, Dave Thirumalai

This study shows water-mediated interactions between neutral N-glycans are weakly repulsive and long-ranged, with decay following a logarithmic pattern.

Journal of the American Chemical Society · May 13, 2025Peer-reviewedBiophysics