Yonathan Goldtzvik

The paper expands the AlphaFold Protein Structure Database to include proteome-scale quaternary structures, predicting 1.81M high-confidence protein complexes and revealing conserved structural clusters across domains of life.

The paper investigates how lever arm flexibility affects coupling to the motor domain in dimeric myosin motors using theoretical models and chimeric constructs.

The paper predicts human and viral protein variants that enhance SARS-CoV-2 binding affinity and may increase COVID-19 susceptibility.

This study shows that hydrodynamic interactions are essential for accurately simulating kinesin's stepping kinetics, as their exclusion leads to drastically reduced stepping efficiency.