BioinformaticsNature CommunicationsPeer-reviewed
Comprehensive detection and characterization of human druggable pockets through novel binding site descriptors
Arnau Comajuncosa-Creus, Guillem Jorba, Xavier Barril, Patrick Aloy
The paper introduces PocketVec, a method to generate binding site descriptors for proteins, identifies over 32,000 druggable pockets in the human proteome, and shows its utility in discovering similar pockets not detected by traditional methods.
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