Inhibition of the transcription factor PU.1 suppresses tumor growth in mice by promoting the recruitment of cytotoxic lymphocytes through the CXCL9-CXCR3 axis
Nichita Sleapnicov, Soon-Duck Ha, Shanshan Jenny Zhong, Jackie Duchscher, Sally Ezra, Shawn S.‐C. Li, Sung Ouk Kim
This study shows that inhibiting PU.1 in mice reduces tumor growth by increasing cytotoxic lymphocyte recruitment via the CXCL9-CXCR3 axis.
Cancers · Aug 18, 2025Peer-reviewedImmunology