Tipping point in α-synuclein-membrane interactions: stable protein-covered vesicles or amyloid aggregation
Katarzyna Makasewicz, Göran Carlström, Olof Stenström, Katja Bernfur, Simon Fridolf, Mikael Akke, Sara Snogerup Linse, Emma Sparr
This study investigates how lipid membranes influence the equilibrium between free and membrane-bound α-synuclein and its amyloid formation, revealing conditions that promote or inhibit aggregation.
Cell Reports Physical Science · Dec 1, 2024Peer-reviewedBiochemistry