Author

Lei Frank Huang

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-0322-6078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Xingxin PaniD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJul 19, 2022

Cell-type-specific aberrant R-loop accumulation regulates target gene and confers cell-specificity

Xingxin Pan, Lei Frank Huang

The paper identifies aberrant R-loops across physiological conditions, develops a deep learning framework to distinguish them from normal R-loops, and links them to cell-specific gene regulation and cancer.

DOI 10.1101/2022.07.19.500727

humanDNA methylation

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