Author

Lan Xiao

National Institutes of HealthORCID 0000-0002-0391-6909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel T. Abebe· 1 shared Pranav SharmaiD· 1 shared Xuyu Yang· 1 shared Y. Peng LohiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Daniel T. Abebe

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1 paper

Recent·Most cited

Neurotrophic Factor-α1/carboxypeptidase E regulates critical protein networks to rescue neurodegeneration, defective synaptogenesis and impaired autophagy in Alzheimer's Disease mice

Lan Xiao, Pranav Sharma, Xuyu Yang, Daniel T. Abebe, Y. Peng Loh

This paper investigates the effects of NF-1/CPE gene therapy in AD mice, finding it prevents memory loss and reverses pathology by modulating protein networks involved in synaptogenesis, autophagy, and tau/Aβ accumulation.

Translational Neurodegeneration · Nov 26, 2025Peer-reviewedNeuroscience