BioinformaticsGenomics & InformaticsPeer-reviewed
Fast and accurate short read alignment with hybrid hash-tree data structure
Junichiro Makino, Toshikazu Ebisuzaki, Ryutaro Himeno, Yoshihide Hayashizaki
The paper introduces a hybrid hash-tree algorithm for short read alignment, achieving 4.4x speed improvement over bwa-mem while maintaining similar accuracy.
16 citations