Author

Pekka Orponen

Aalto UniversityORCID 0000-0002-0417-2104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander IliniD· 1 shared Björn HögbergiD· 1 shared Giulio BernardinelliiD· 1 shared Ian T. HoffeckeriD· 1 shared Mehdi Saman BooyiD· 1 shared Vo Hong ThanhiD· 1 shared Yunshi YangiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 7 mutual co-author links

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1 shared paperBioinformatics

Alexander IlinORCID

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3 papers

Recent·Most cited

RNA secondary structure prediction with Convolutional Neural Networks

Mehdi Saman Booy, Alexander Ilin, Pekka Orponen

This paper introduces a convolutional neural network for RNA secondary structure prediction, achieving significant accuracy improvements over existing methods.

BMC Bioinformatics · Feb 2, 2022Peer-reviewedBioinformatics

Cotranscriptional kinetic folding of RNA secondary structures

Vo Hong Thanh, Pekka Orponen

The paper introduces a kinetic model for cotranscriptional RNA folding and demonstrates its ability to predict metastable conformations.

bioRxiv · Jul 10, 2020 · PreprintBioinformatics

A Computational Framework for DNA Sequencing-Based Microscopy

Ian T. Hoffecker, Yunshi Yang, Giulio Bernardinelli, Pekka Orponen, Björn Högberg

The paper introduces a computational framework to reconstruct spatial information from DNA sequencing data by analyzing polony adjacency networks.

bioRxiv · Nov 21, 2018 · PreprintBiophysics