Shaping the Glycan Landscape: Hidden relationships between linkage and ring distortions induced by carbohydrate-active enzymes
Isabell Louise Grothaus, Paul Spellerberg, Carme Rovira, Lucio Colombi Ciacchi
This study investigates how carbohydrate-active enzymes induce conformational changes in glycans through ring distortions, revealing mechanisms that influence enzyme specificity and inhibitor design.
Journal of the American Chemical Society · Oct 9, 2025Peer-reviewedBiophysics