Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury
Qing Chuan Zhao, Yanjing Zhu, Yilong Ren, Lijuan Zhao, Jingwei Zhao, Shuai Yin, Haofei Ni, Rongrong Zhu, Liming Cheng, Ning Xie
This study shows that selectively eliminating resident astrocytes in lumbar enlargement reduces neuropathic pain after spinal cord injury by activating the type I IFNs signal in microglia.
eLife · Nov 7, 2024Peer-reviewedNeuroscience