Developmental BiologyNature CommunicationsPeer-reviewed
TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiation
Jianfang Li, Xinwei Wu, Jie Ke…·Ruiyu Xie
This study shows TET1 is essential for FOXA2-mediated chromatin remodeling in pancreatic beta-cell differentiation by rescuing differentiation defects and restoring PAX4 hypomethylation.