Author

Zhengzheng Zhang

Leiden UniversityORCID 0000-0002-0537-3506Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Alida S. D. KindtiD· 2 shared Amy C. HarmsiD· 2 shared Thomas HankemeieriD· 2 shared Ahmed AliiD· 1 shared Annelien J.M. ZweemeriD· 1 shared Charlotte Nijgh van Kooij· 1 shared Diederik A M P J GommersiD· 1 shared Hanneke LeegwateriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Alida S. D. KindtORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 12, 2025

Metabolic Signatures of Pulmonary Embolism in COVID-19: Insights from Longitudinal Intensive Care Unit Profiles

Mark Valdez, Malou Janssen, Zhengzheng Zhang…·Thomas Hankemeier

This study identifies metabolic signatures associated with pulmonary embolism in COVID-19 patients using longitudinal ICU data, revealing key lipid and amine changes post-event.

DOI 10.1101/2025.09.12.675971

humanmetabolomics

𝕏 PostBluesky

BioinformaticsJournal of ChemometricsPeer-reviewedDec 8, 2024

Normalization strategies for lipidome data in cell line panels

Hanneke Leegwater, Zhengzheng Zhang, Xiaobing Zhang…·Alida S. D. Kindt

This study evaluates normalization strategies for lipidomic data in cell line panels, finding that data-based approaches improve replicate similarity but may introduce artifacts.

10 citations

metabolomicsstatistical model

𝕏 PostBluesky