Jaxley: Differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics
Michael Deistler, Kyra L. Kadhim, Matthijs Pals, Jonas Beck, Ziwei Huang, Manuel Gloeckler, Janne K. Lappalainen, Cornelius Schröder, Philipp Berens, Pedro J. Gonçalves, Jakob H. Macke
The paper introduces JO_SCPLOWAXLEYC_SCPLOW, a framework for differentiable simulation of biophysical neuron models, enabling efficient parameter optimization and task-driven training of large-scale models.
Nature Methods · Nov 13, 2025Peer-reviewedNeuroscience