Reduced plasticity in coupling strength in the SCN clock in aging as revealed by Kuramoto modelling
Anouk W. van Beurden, Janusz M Meylahn, Stefan Achterhof, Johanna H. Meijer, Jos H. T. Rohling
This study uses Kuramoto modeling to show that aging reduces the ability of SCN neurons to adjust coupling strength in response to photoperiod changes, impairing seasonal adaptation.
bioRxiv · Sep 13, 2021 · PreprintNeuroscience