Johanna H. Meijer

This study identifies eight small-molecule enhancers of circadian rhythm amplitude in both central and peripheral clocks through a drug repurposing screen and ex vivo validation.

The paper examines how physical activity affects the circadian clock in diurnal rodents, finding that activity increases SCN neuronal firing rather than suppressing it, unlike in nocturnal animals.

This study directly measures the light response of the human SCN and finds that light suppresses SCN activity across multiple wavelengths, suggesting a need to revise light exposure strategies.

This study uses Kuramoto modeling to show that aging reduces the ability of SCN neurons to adjust coupling strength in response to photoperiod changes, impairing seasonal adaptation.