Olga Ibáñez-Solé

The paper develops tools to quantify transcriptional noise in aging tissues and finds no universal increase in noise, but detects age-related changes in cell type composition.

The paper shows that aging and lifestyle factors cause genotoxic damage, leading to reduced transcription of long genes across multiple species and tissues.

Triku selects genes defining main cell populations in single-cell data by prioritizing genes expressed in closely grouped cells.