Linking Codon- and Protein-Level Mutation Scores to Population Genetics Reveals Heterogeneous Selection Efficiency Across Escherichia coli Lineages
Manolo Mischler, Lucile Vigué, Giancarlo Croce, Martin Weigt, Olivier Tenaillon
The paper quantifies selection efficiency across Escherichia coli lineages by linking mutation scores to population genetics, showing significant variation in selection intensity between synonymous and non-synonymous mutations and pathogenic populations.
bioRxiv · Mar 18, 2026 · PreprintGenetics