Spike Antibody Fc Drives Protection from SARS-CoV-2 Challenge in Macaques
Caolann Brady, Melissa Govender, Jack Mellors, Tom Tipton, Karen E. Gooch, Adriana Tomić, Miles W. Carroll
This study identifies spike antibody features, including Fc{gamma}R binding and complement deposition, as strong correlates of protection against SARS-CoV-2 in macaques.
bioRxiv · Mar 13, 2026 · PreprintImmunology