Author

Patrik Rydén

Umeå UniversityORCID 0000-0002-0577-123XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christina E. WestiD· 1 shared David KällbergiD· 1 shared Kushan De SilvaiD· 1 shared Linda VidmaniD· 1 shared Magnus DomellöfiD· 1 shared Marie‐Therese VinnarsiD· 1 shared Olivier KeechiD· 1 shared Rafael Björk· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Christina E. WestORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 1, 2025

Epigenetic mediation may explain intergenerational associations between maternal lifestyle and birth weight of offsprings - Findings from the NorthPop prospective birth cohort

Kushan De Silva, Richard Lundberg Ulfsdotter, Stina Bodén…·Sophia Harlid

The paper investigates how maternal lifestyle factors affect offspring birth weight through epigenetic mediation using the NorthPop cohort.

DOI 10.1101/2025.06.01.25328723

humanDNA methylation

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BioinformaticsPLoS ONEPeer-reviewedDec 5, 2019

Cluster analysis on high dimensional RNA-seq data with applications to cancer research- An evaluation study

Linda Vidman, David Källberg, Patrik Rydén

This study evaluates how cluster analysis choices affect cancer subtype identification using four human cancer datasets, finding that sample size has limited impact while heterogeneity and subtype distribution significantly influence performance.

34 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintJun 27, 2019

Enhancing the biological relevance of Gene Co-expression Networks: A plant mitochondrial case study

Simon R. Law, Therese G. Kellgren, Rafael Björk…·Olivier Keech

The paper introduces a method to improve the biological relevance of gene co-expression networks by centering data within sub-experiments, validated using plant mitochondrial proteome data.

1 citation

plant (other)bulk RNA-seq

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