Author

Dean R. Tolan

Boston UniversityORCID 0000-0002-0598-7241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Ashley M RebeloiD· 1 shared Karen N. AlleniD· 1 shared Lanlan HaniD· 1 shared Nemanja VuksanoviciD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Ashley M RebeloORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 10, 2026

Deciphering AMP deaminase-2 structure, activators and regulators underpinning cellular function in human fructose and nucleotide metabolism

Ashley M Rebelo, Nemanja Vuksanovic, Lanlan Han…·Karen N. Allen

This study characterizes the structure and regulation of hAMPD2-2, revealing ATP activation, GTP inhibition, and Pi's role in modulating the enzyme under physiological and fructose conditions.

DOI 10.64898/2026.06.10.731346

humanprotein structure