HIV and Cocaine exposure promote Tau phosphorylation through RSK-1 in a GSK3β-independent manner.
Adhikarimayum Lakhikumar Sharma, Ilker Kudret Sariyer, Ulhas Pandurang Naik, Mudit Tyagi
This study identifies RSK1 as a central mediator of Tau phosphorylation in response to HIV and cocaine exposure, revealing a GSK3β-independent mechanism.
bioRxiv · Apr 16, 2026 · PreprintMolecular Biology