Interplay of human macrophage response and natural resistance of L. (V.) panamensis to pentavalent antimony
Olga Lucía Fernández, Ashton T. Belew, Mariana Rosales-Chilama, Andrea Sánchez-Hidalgo, Marı́a Colmenares, Nancy Gore Saravia, Najib M. El-Sayed
This study shows that naturally resistant L. (V.) panamensis strains induce distinct macrophage responses compared to sensitive strains, even in the presence of antimony, highlighting host-parasite interactions in drug resistance.
PLoS neglected tropical diseases · Oct 6, 2025Peer-reviewedImmunology