Recent fluctuations in Mexican American genomes have altered the genetic architecture of biomedical traits
Melissa L. Spear, Alex Diaz-Papkovich, Elad Ziv, Joseph Yracheta, Simon Gravel, Dara G. Torgerson, Ryan D. Hernandez
The paper shows that increased Amerindigenous ancestry in Mexican Americans over time has altered the genetic architecture of traits like height and polygenic risk scores.
eLife · Dec 29, 2020Peer-reviewedGenetics