A single cell framework for multi-omic analysis of disease identifies malignant regulatory signatures in mixed phenotype acute leukemia
Jeffrey M. Granja, Sandy L. Klemm, Lisa M. McGinnis, Arwa S. Kathiria, Anja Mezger, Benjamin E. Parks, Eric J. Gars, Michaela Liedtke, Grace X. Y. Zheng, Howard Y. Chang, Ravindra Majeti, William James Greenleaf
This paper develops a single-cell multi-omic framework to identify malignant regulatory signatures in mixed phenotype acute leukemia by analyzing transcriptomic and epigenetic data.
bioRxiv · Jul 9, 2019 · PreprintGenomics