This study benchmarks four kinship estimation tools for ancient genomes using simulated pedigrees and finds varying accuracy depending on the tool and SNP count.

Molecular Ecology Resources · Apr 27, 2024Peer-reviewedGenetics

A genomic snapshot of demographic and cultural dynamism in Upper Mesopotamia during the Neolithic Transition

N. Ezgi Altınışık, Duygu Deniz Kazancı, Ayça Aydoğan, Hasan Can Gemici, Ömür Dilek Erdal, Savaş Sarıaltun, Kıvılcım Başak Vural, Dilek Koptekin, Kanat Gürün, Ekin Sağlıcan, Daniel Fernandes, Gökhan Çakan, Meliha Melis Koruyucu, Vendela Kempe Lagerholm, Cansu Karamurat, , Mehmet Somel

This study analyzes ancient genomes from Upper Mesopotamia during the Neolithic Transition, revealing genetic diversity, immigration, and cultural practices such as head-shaping.

Science Advances · Nov 4, 2022Peer-reviewedGenetics

Human inbreeding has decreased in time through the Holocene

Francisco C. Ceballos, Kanat Gürün, N. Ezgi Altınışık, Hasan Can Gemici, Cansu Karamurat, Dilek Koptekin, Kıvılcım Başak Vural, Igor Mapelli, Ekin Sağlıcan, Elif Sürer, Yılmaz Selim Erdal, Anders Götherström, Füsun Özer, Çiğdem Atakuman, Mehmet Somel

This study shows inbreeding frequency decreased over time in ancient Eurasian populations, linked to population growth from agricultural practices.

Current Biology · Jul 2, 2021Peer-reviewedGenomics