Botond B. Antal

Computational modeling of neurotransmitter cycling predicts human brain glutamate and GABA dynamics in response to administration of exogenous ketones

This study develops a computational model of neurotransmitter cycling to predict glutamate and GABA dynamics in response to exogenous ketones, supported by MRS data.

Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study

This study uses 1H MR Spectroscopy and rsfMRI to show that ketosis increases antioxidants and energy markers while improving neural function through enhanced bioenergetics.

Spatially convergent fMRI signatures of diabetes and male sex identify genetic vulnerabilities to accelerated brain aging

Brain signaling becomes less integrated and more segregated with age

The paper defines brain integration and segregation using the Ising model to analyze functional MRI data, finding that these states become less balanced with age.

D--hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.

This study examines how D--hydroxybutyrate affects hippocampal circuit function during acute insulin resistance in mice, showing it rescues neuronal activity and synaptic function.

Metabolism modulates network synchrony in the aging brain

This study shows that aging reduces brain network synchrony, modeled as a critical point in communication strength, and demonstrates that metabolic changes can drive these global shifts.