Author

Tianchi Chen

Northeastern UniversityORCID 0000-0002-0779-0143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Christopher A. VoigtiD· 2 shared Eduardo D. SontagiD· 2 shared M. Ali Al-RadhawiiD· 2 shared Anh Phong TraniD· 1 shared Bogdan BudnikiD· 1 shared Dmitry MalioutoviD· 1 shared Edoardo M. AiroldiiD· 1 shared Elizabeth Ann Ernst· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersSynthetic Biology

Christopher A. VoigtORCID

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3 papers

Recent·Most cited

A synthetic distributed genetic multi-bit counter

Tianchi Chen, M. Ali Al-Radhawi, Christopher A. Voigt, Eduardo D. Sontag

This paper designs a synthetic genetic multi-bit counter using repressor-based circuits that can count input pulses modulo 2^N.

iScience · Nov 29, 2021Peer-reviewedSynthetic Biology

Distributed implementation of Boolean functions by transcriptional synthetic circuits

M. Ali Al-Radhawi, Anh Phong Tran, Elizabeth Ann Ernst, Tianchi Chen, Christopher A. Voigt, Eduardo D. Sontag

This paper develops a method to synthesize distributed Boolean circuits using diffusible small molecules, enabling scalable computation beyond single-cell limitations.

ACS Synthetic Biology · Jun 26, 2020Peer-reviewedSynthetic Biology

Quantifying homologous proteins and proteoforms

Dmitry Malioutov, Tianchi Chen, Jacob D. Jaffe, Edoardo M. Airoldi, Steve Carr, Bogdan Budnik, Nikolai Slavov

The paper develops a model to accurately quantify proteoform stoichiometries using mass-spectrometry data without external standards.

Molecular & Cellular Proteomics · Oct 3, 2018Peer-reviewedSystems Biology