Author

Romit Bhattacharya

Broad InstituteORCID 0000-0002-0782-4753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abhishek NiroulaiD· 2 shared Alexander G. BickiD· 2 shared Barry I. FreedmaniD· 2 shared Bertha HidalgoiD· 2 shared Braxton D. MitchelliD· 2 shared Brian CusteriD· 2 shared Christopher James GibsoniD· 2 shared Dawood DarbariD· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Abhishek NiroulaORCID

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2 papers

Recent·Most cited

Genomic and phenomic landscape of clonal hematopoiesis in over a million ancestrally diverse participants

Md Mesbah Uddin, Zhi Yu, Joshua S. Weinstock, Abhishek Niroula, Caitlyn Vlasschaert, Satoshi Koyama, Tetsushi Nakao, Sarah Urbut, Seyedeh Maryam Zekavat, Kaavya Paruchuri, Buu Minh Thanh Truong, Alexander James Silver, Taralynn Mack, Megan Y. Wong, Sara Haidermota, , Pradeep Natarajan

This study analyzes clonal hematopoiesis in over a million diverse individuals, identifying 72 genome-wide significant loci and linking CHIP to various phenotypes.

medRxiv · Jul 29, 2022 · PreprintGenetic & Genomic Medicine

Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

Tetsushi Nakao, Alexander G. Bick, Margaret A. Taub, Seyedeh Maryam Zekavat, Md Mesbah Uddin, Abhishek Niroula, Cara L. Carty, John Lane, Michael C. Honigberg, Joshua S. Weinstock, Akhil Pampana, Christopher James Gibson, Gabriel Kenneth Griffin, Shoa L. Clarke, Romit Bhattacharya, , Brian Custer

The paper uses bidirectional Mendelian randomization to show LTL lengthening increases CHIP risk, while CHIP accelerates LTL shortening, with modest mediation between CHIP and CAD via LTL.

Science Advances · Apr 6, 2022Peer-reviewedGenetic & Genomic Medicine