Identifying potential therapeutic targets for T-cell acute lymphoblastic leukemia using malignant networks and topological analysis
Rodrigo Henrique Ramos, Nicolas Carels, Rafaela Scardini, Leticia Lopes Franca, Adenilso Da Silva Simao, Cynthia de Oliveira Lage Ferreira, Flávia Raquel Gonçalves Carneiro
This study identifies potential therapeutic targets for T-ALL by analyzing topological properties of protein-protein interaction networks and evaluating gene essentiality through network attack strategies.
bioRxiv · Oct 8, 2025 · PreprintCancer Biology