Author

David Calderwood

ORCID 0000-0002-0791-4142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Aleksander DurumericiD· 1 shared Anirban Polley· 1 shared Daniel Iwamoto· 1 shared Gregory A VothiD· 1 shared Martin A. Schwartz· 1 shared Tamara C. Bidone· 1 shared Tristan Driscoll· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Aleksander DurumericORCID

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1 paper

Recent·Most cited

New Insights into the Conformational Activation of Full-Length Integrin

Tamara C. Bidone, Anirban Polley, Aleksander Durumeric, Tristan Driscoll, Daniel Iwamoto, David Calderwood, Martin A. Schwartz, Gregory A Voth

This study investigates integrin conformational activation pathways using simulations and experiments, supporting a 'deadbolt' model over a 'switchblade-like' mechanism.

bioRxiv · Oct 15, 2017 · PreprintBiophysics