Repeated toxic injuries of murine liver are tolerated through microsteatosis and mild inflammation
Seddik Hammad, Christoph Ogris, Amnah Othman, Pia Erdoesi, Wolfgang Schmidt‐Heck, Ina Biermayer, Barbara Helm, Yan Lin Gao, Weronika Piorońska, Lorenza A. D’Alessandro, Fabian Joachim Theis, Matthias P. Ebert, Ursula Klingmüller, Jan Georg Hengstler, Steven Dooley, Nikola S. Mueller
This study identifies microsteatosis and mild inflammation as key features of liver tolerance to repeated toxic injuries, using a mouse model and multi-omics analysis.
bioRxiv · Jan 12, 2022 · PreprintSystems Biology