Functional heterogeneity and plasticity in naive CD8 T cells drive superior effector and memory responses
Yamato Sajiki, Satomi Ando, Charles M. Perkins, Yi-Chung Huang, Katie E. Smith, Carolyn M. Doerning, David A. Hildeman, Koichi Araki
The paper identifies functional heterogeneity and plasticity in naive CD8 T cells, showing high-quality subsets can drive superior immune responses through enhanced effector cell survival.
The Journal of Experimental Medicine · Aug 12, 2026Peer-reviewedImmunology