Author

Jordan S. Lane

ORCID 0000-0002-0853-7457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Layla Hosseini-GeramiiD· 1 shared Sara MasaroneiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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1 shared paperSystems Biology

Layla Hosseini-GeramiORCID

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1 paper

Recent·Most cited

Using SAFEPATH to Uncover a Novel Mechanism of Hepatotoxicity for Gefitinib

Layla Hosseini-Gerami, Sara Masarone, Jordan S. Lane

This study uses SAFEPATH to identify a novel sphingolipid metabolism mechanism of Gefitinib toxicity and validate it experimentally, while recovering the known UGT1A1-mediated toxicity of Erlotinib.

bioRxiv · Jul 31, 2024 · PreprintSystems Biology