Cancer BiologybioRxivPreprint
An IGF2-anchored oncofetal state and relapse-associated transcriptomic module define systemic progression risk in early-onset colorectal cancer
Elena Licitra-Rosa, Giulia Mantini, Federica Persiani…·Ruggero De Maria
This paper identifies an IGF2-driven oncofetal state and a 5-gene module that predict systemic relapse in early-onset colorectal cancer, improving risk stratification beyond traditional staging.
DOI 10.64898/2026.05.18.725955