NeurosciencebioRxivPreprint
The SEA-AD DREAM Challenge: Community benchmarking human and AI agent solutions for Alzheimer's disease neuropathology prediction from single-nucleus transcriptomics
Hsin-Yu Lai, Nikolaos Kalavros, Verena Chung…·Mariano I. Gabitto
The paper presents a benchmarking challenge to predict Alzheimer's disease neuropathology from single-nucleus transcriptomics using human and AI models, finding that top methods achieve near-perfect categorical staging predictions.