Author

Mitchell K. Higashi

Sema4 (United States)ORCID 0000-0002-1047-0263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alan Barry Copperman· 1 shared Ashley H. Birch· 1 shared Bryn D. WebbiD· 1 shared Eric E. SchadtiD· 1 shared Jonathan TyleriD· 1 shared Li LiiD· 1 shared Lisa J. EdelmanniD· 1 shared Lisa Y. Lau· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alan Barry Copperman

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1 paper

Recent·Most cited

Real-world genetic screening with molecular ancestry supports comprehensive pan-ethnic carrier screening

Ryan A. Shewcraft, Mitchell K. Higashi, Yeting Zhang, Jonathan Tyler, Lisa Y. Lau, Bryn D. Webb, Seungwoo Lee, Rajasekar Ramasamudram-Chakravarthi, Teresa A. Cacchione, Alan Barry Copperman, Ashley H. Birch, Marra S. Francis, Lisong Shi, Lisa J. Edelmann, Rong Chen, , Eric E. Schadt

The paper evaluates a comprehensive pan-ethnic carrier screening panel across 282 monogenic diseases in 397,540 patients, showing it identifies 10-times more at-risk carrier couples than a two-gene panel and provides cost savings.

medRxiv · Sep 2, 2022 · PreprintGenetic & Genomic Medicine