Jonathan Tyler

The paper evaluates a comprehensive pan-ethnic carrier screening panel across 282 monogenic diseases in 397,540 patients, showing it identifies 10-times more at-risk carrier couples than a two-gene panel and provides cost savings.

The paper develops a method to infer causality in oscillatory biological systems, outperforming existing methods and providing a computational tool for analysis.

The paper uses daylight saving time as a natural experiment to study how genetic variation influences adaptation to abrupt time changes, finding differential effects based on morning or evening genetic predisposition.