Bioactivity-driven discovery of repurposable antivirals as OSCAR inhibitors that promote cartilage protection via transcriptomic reprogramming
Gina Ryu, Jihee Kim, Sera Park, Soo Young Lee, Wankyu Kim
The paper identifies adefovir and brivudine as OSCAR inhibitors that reduce OA progression and promote cartilage protection through transcriptomic changes in a mouse model.
bioRxiv · Feb 25, 2026 · PreprintBioinformatics