Julian Kreis

Stromal signals dominate gene expression signature scores that aim to describe cancer-intrinsic stemness or mesenchymality characteristics

The paper shows that stromal cells, particularly fibroblasts, dominate EMT-related gene expression signature scores in cancer, rather than tumor-intrinsic properties.

Feature selection strategies for drug sensitivity prediction

The paper evaluates feature selection strategies for drug sensitivity prediction, finding that prior knowledge-based methods outperform genome-wide approaches for drugs targeting specific genes and pathways.