Engineering Microbial R- and S- β-Hydroxybutyrate Production
Burak Kizil, Sinem Ulusan, Aydan Torun, Mehmet Gümüştaş, Seniz Yüksel, Sreeparna Banerjee
This study engineers E. coli to produce high-yield, enantiomerically pure β-hydroxybutyrate (BHOB) for therapeutic applications in cancer and gut-brain disorders.
bioRxiv · Jul 15, 2025 · PreprintSynthetic Biology